New World arenaviruses are pathogens capable of zoonotic infections that cause viral haemorrhagic fevers, which are frequently lethal in humans. However, a recombinant live-attenuated pentavalent vaccine shows promising efficacy against infection.
References
Warner, B. M., Safronetz, D. & Stein, D. R. Drug Des. Devel. Ther. 12, 2519–2527 (2018).
Sarute, N. & Ross, S. R. Annu. Rev. Virol. 4, 141–158 (2017).
Maiztegui, J. I. et al. J. Infest. Dis. 177, 277–283 (1998).
Mateo, M. et al. Sci. Transl. Med. 11, 3163 (2019).
Carnec, X. et al. J. Virol. https://doi.org/10.1128/JVI.02230-17 (2018).
Reynard, S. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-022-01281-y (2023).
Clark, L. E. et al. Nat. Commun. 9, 1884 (2018).
Sommerstein, R. et al. PLoS Pathog. 11, e1005276 (2015).
Zaza, A. D., Herbreteau, C. H. & Peyrefitte, C. N. Virol. J. 15, 99 (2018).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Prévost, J., Warner, B.M. & Safronetz, D. Multitasking to prevent viral haemorrhagic fevers. Nat Microbiol 8, 8–9 (2023). https://doi.org/10.1038/s41564-022-01296-5
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41564-022-01296-5
- Springer Nature Limited