Two studies now identify bradyzoite-formation deficient 1 and microrchidia as ‘master regulators’ of the transcriptional events that control developmental life cycle transitions in the protozoan parasite Toxoplasma gondii.
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References
Martynowicz, J., Augusto, L., Wek, R. C., Boehm, S. L. II & Sullivan, W. J. Jr. mBio 10, e00381-19 (2019).
Tyebji, S., Seizova, S., Hannan, A. J. & Tonkin, C. J. Neurosci. Biobehav. Rev. 96, 72–92 (2019).
Dixon, S. E., Stilger, K. L., Elias, E. V., Naguleswaran, A. & Sullivan, W. J. Jr Mol. Biochem. Parasitol. 173, 1–9 (2010).
Balaji, S., Babu, M. M., Iyer, L. M. & Aravind, L. Nucleic Acids Res. 33, 3994–4006 (2005).
Painter, H. J., Campbell, T. L. & Llinas, M. Mol. Biochem. Parasitol. 176, 1–7 (2011).
Gissot, M., Briquet, S., Refour, P., Boschet, C. & Vaquero, C. J. Mol. Biol. 346, 29–42 (2005).
Jeffers, V., Tampaki, Z., Kim, K. & Sullivan, W. J. Jr Cell. Mol. Life Sci. 75, 2355–2373 (2018).
Waldman, B. S. et al. Cell 180, 359–372 (2020).
Farhat, D. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-020-0674-4 (2020).
Holmes, M. J., Augusto, L. D. S., Zhang, M., Wek, R. C. & Sullivan, W. J. Jr Trends Parasitol. 33, 947–960 (2017).
Hunter, C. A. et al. Nat. Rev. Microbiol. 10, 766–778 (2012).
Frenal, K. et al. Nat. Rev. Microbiol. 15, 645–660 (2017).
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Sullivan, W.J. Mastering Toxoplasma sex and sleep. Nat Microbiol 5, 533–534 (2020). https://doi.org/10.1038/s41564-020-0696-y
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DOI: https://doi.org/10.1038/s41564-020-0696-y
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