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Bacterial Pathogenesis

Silence is golden for Staphylococcus

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Biofilms are communities of bacteria that accumulate on surfaces such as replacement joints or intravenous catheters. By silencing a key communication system, Staphylococcus aureus builds tightly packed biofilms that can withstand attack by host immune cells.

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Fig. 1: A model for Agr in biofilm-associated disease.

References

  1. Le, K. Y. & Otto, M. Front. Microbiol. 6, 1174 (2015).

    Article  Google Scholar 

  2. He, L. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-019-0413-x (2019).

    Article  PubMed  Google Scholar 

  3. Cheung, G. Y., Wang, R., Khan, B. A., Sturdevant, D. E. & Otto, M. Infect. Immun. 79, 1927–1935 (2011).

    Article  CAS  Google Scholar 

  4. Boles, B. R. & Horswill, A. R. PLoS Pathog. 4, e1000052 (2008).

    Article  Google Scholar 

  5. Periasamy, S. et al. Proc. Natl Acad. Sci. USA 109, 1281–1286 (2012).

    Article  CAS  Google Scholar 

  6. Recker, M. et al. Nat. Microbiol. 2, 1381–1388 (2017).

    Article  CAS  Google Scholar 

  7. Bhattacharya, M. et al. Proc. Natl Acad. Sci. USA 115, 7416–7421 (2018).

    Article  CAS  Google Scholar 

  8. Painter, K. L., Krishna, A., Wigneshweraraj, S. & Edwards, A. M. Trends Microbiol. 22, 676–685 (2014).

    Article  CAS  Google Scholar 

  9. Parlet, C. P. et al. Cell Rep. 27, 187–198 (2019).

    Article  CAS  Google Scholar 

Download references

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  1. MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, UK

    Andrew M. Edwards

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  1. Andrew M. Edwards
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Correspondence to Andrew M. Edwards.

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Edwards, A.M. Silence is golden for Staphylococcus. Nat Microbiol 4, 1073–1074 (2019). https://doi.org/10.1038/s41564-019-0493-7

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