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Microbiome genome structure drives function

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Differences in microbial genomes can result in vastly different phenotypes and functions. Consequently, it is critical to understand the genome variations that differentiate microbial strains. Here, we discuss recent exciting advances that enable structural variant measurement, their associated phenotypes and the horizon for future discovery.

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Fig. 1: Structural variation in the gut microbiome.

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Authors and Affiliations

  1. Department of Genetics, Stanford University, Stanford, CA, USA

    Matthew G. Durrant & Ami S. Bhatt

  2. Division of Hematology, Blood and Marrow Transplantation, Department of Medicine, Stanford University, Stanford, CA, USA

    Ami S. Bhatt

Authors
  1. Matthew G. Durrant
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  2. Ami S. Bhatt
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Corresponding author

Correspondence to Ami S. Bhatt.

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The authors declare no competing interests.

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Durrant, M.G., Bhatt, A.S. Microbiome genome structure drives function. Nat Microbiol 4, 912–913 (2019). https://doi.org/10.1038/s41564-019-0473-y

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  • DOI: https://doi.org/10.1038/s41564-019-0473-y

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