The early identification of repetitive genomic loci in Haloferax species was instrumental in igniting interest in CRISPR–Cas systems. Now, work in this genus has revealed an important role of CRISPR–Cas in reducing an unusual form of inter-species archaeal mating that occurs by cell fusion.
References
Jackson, S. A. et al. Science 365, eaal5056 (2017).
Marraffini, L. A. & Sontheimer, E. J. Science 322, 1843–1845 (2008).
Watson, B. N. J., Staals, R. H. J. & Fineran, P. C. mBio 9, e02406-17 (2018).
Rosenshine, I., Tchelet, R. & Mevarech, M. Science 245, 1387–1389 (1989).
Noar, A. et al. Curr. Biol. 22, 1444–1448 (2012).
Shalev, Y. et al. Front. Microbiol. 8, 1253 (2017).
Turgeman-Grott, I. et al. Nat. Microbiol. https://doi.org/s41564-018-0302-8 (2018).
Brodt, A., Lurie-Weinberger, M. N. & Gophna, U. Biol. Direct 6, 65 (2011).
Silas, S. et al. eLife 6, e27601 (2017).
Patterson, A. G. et al. Molec. Cell 64, 1102–1108 (2016).
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Fineran, P.C. CRISPR–Cas impedes archaeal mating. Nat Microbiol 4, 2–3 (2019). https://doi.org/10.1038/s41564-018-0326-0
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DOI: https://doi.org/10.1038/s41564-018-0326-0
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