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VIRAL INFECTION

Cheese, phages and anti-CRISPRs

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The study of phages that pose a threat to the cheese industry, which enabled the original demonstration that CRISPR–Cas systems work as adaptive immune systems in bacteria, now leads to the identification of a new anti-CRISPR that inhibits Cas9 from Streptococcus pyogenes.

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Fig. 1: Phage-based functional screen for identifying new anti-CRISPRs.

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Correspondence to Alan R. Davidson.

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Davidson, A.R. Cheese, phages and anti-CRISPRs. Nat Microbiol 2, 1338–1339 (2017). https://doi.org/10.1038/s41564-017-0026-1

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