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Cancer immunotherapy

A thicker skin for better immune evasion

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Cancer cells adjust the composition of their glycocalyx to increase its thickness and create a physical barrier that shields them from immune recognition and engagement.

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Fig. 1: Cancer cells create a protective glycocalyx shield against immune cells.

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Authors and Affiliations

  1. Deparment of Chemistry, University of Alberta, Edmonton, Alberta, Canada

    Edward N. Schmidt & Matthew S. Macauley

  2. Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada

    Matthew S. Macauley

  3. Neuroscience and Mental Health Institute, Edmonton, Alberta, Canada

    Matthew S. Macauley

Authors
  1. Edward N. Schmidt
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  2. Matthew S. Macauley
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Correspondence to Matthew S. Macauley.

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The authors declare no competing interests.

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Schmidt, E.N., Macauley, M.S. A thicker skin for better immune evasion. Nat. Mater. 23, 312–313 (2024). https://doi.org/10.1038/s41563-024-01822-2

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