The concepts of multistep processes and regioselectivity — fundamental in covalent synthesis — have now been applied to the non-covalent synthesis of sequence-controlled multiblock supramolecular polymers.
References
Lehn, J.-M. Supramolecular Chemistry: Concepts and Perspectives (Wiley, 1995).
Whitesides, G. M. & Grzybowski, B. Science 295, 2418–2421 (2002).
Vantomme, G. & Meijer, E. W. Science 363, 1396–1397 (2019).
Baran, P. S. J. Am. Chem. Soc. 140, 4751–4755 (2018).
Sasaki, N. et al. Nat. Chem. https://doi.org/10.1038/s41557-023-01216-y (2023).
Sasaki, N. et al. Nat. Commun. 11, 3578 (2020).
Vonk, K. M., Meijer, E. W. & Vantomme, G. Chem. Sci. 12, 13572–13579 (2021).
Hassner, A. J. Org. Chem. 33, 2684–2686 (1968).
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Vantomme, G. Site selectivity steps in. Nat. Chem. 15, 894–895 (2023). https://doi.org/10.1038/s41557-023-01237-7
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DOI: https://doi.org/10.1038/s41557-023-01237-7
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