The selective removal of one oxygen atom from sulfones, without over-reduction to sulfide, is a challenging task. Now, through organocatalysis and incorporation of a cyano group into the sulfone, an asymmetric deoxygenation strategy has been developed, providing an efficient method for the synthesis of chiral sulfinyl compounds.
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Wojaczyńska, E., Wojaczyński, J. Chiral sulfinyls from sulfones. Nat. Chem. 15, 165–166 (2023). https://doi.org/10.1038/s41557-022-01122-9
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DOI: https://doi.org/10.1038/s41557-022-01122-9
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