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Catalytic coacervate crucibles

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Phase separation offers a fundamental mechanism for organization and compartmentalization. Now, peptide-based synthons have been shown to form catalytically active coacervates providing a stepping stone for creating synthetic primitive cells.

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Fig. 1: Condensation via liquid–liquid phase separation of a short peptide synthon.

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Correspondence to Samrat Mukhopadhyay.

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Mukhopadhyay, S. Catalytic coacervate crucibles. Nat. Chem. 13, 1028–1030 (2021). https://doi.org/10.1038/s41557-021-00815-x

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