Biomolecular condensates are recognized for their ability to compartmentalize the cytoplasm without bounding membranes, but the degree to which they organize the cytoplasm has not been clear. A new study reveals that condensates at a scale of 100 nm are responsible for the organization of at least 18% of the cytoplasmic proteome.
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J.A.D. is an advisor for Dewpoint Therapeutics. L.A.L. declares no competing interests.
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Ahangama Liyanage, L., Ditlev, J.A. Mesoscale condensates organize the cytoplasm. Nat Cell Biol 26, 310–312 (2024). https://doi.org/10.1038/s41556-023-01331-5
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DOI: https://doi.org/10.1038/s41556-023-01331-5
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