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Lipid remodelling in mammalian development

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Lipids have a pivotal role in the growth of oocytes and fertilized eggs. Ultra-sensitive lipidome analysis provides a complete overview of the lipid profile during early embryonic development and brings insights into how dynamic lipid remodelling determines the fate of mammalian embryos.

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Fig. 1: A comprehensive lipidomic analysis of lipids extracted from mouse and human oocytes and embryos reveals the landscape of lipid profiles during preimplantation embryonic development.

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Authors and Affiliations

  1. Laboratory Animal and Genome Sciences Section, National Institutes for Quantum Science and Technology, Chiba, Japan

    Megumi Ibayashi & Satoshi Tsukamoto

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  1. Megumi Ibayashi
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  2. Satoshi Tsukamoto
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Correspondence to Satoshi Tsukamoto.

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The authors declare no competing interests.

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Ibayashi, M., Tsukamoto, S. Lipid remodelling in mammalian development. Nat Cell Biol 26, 179–180 (2024). https://doi.org/10.1038/s41556-023-01327-1

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