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Mechanotransduction

A new cell in an old tactile sensory organ

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In adult Drosophila, the sense of touch is mediated by mechanosensory organs, namely tactile bristles in the epidermis. A new study reveals that a previously unknown type of epidermal cell, named the F-cell, is recruited to ensheath the tactile bristle and is required for touch sensing.

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Fig. 1: Anatomy and development of Drosophila tactile bristle.
Fig. 2: The F-cell is important for the function of the tactile bristle.

References

  1. Lai, E. C. & Orgogozo, V. Dev. Biol. 269, 1–17 (2004).

    Article  CAS  PubMed  Google Scholar 

  2. Kernan, M. J. Pflugers Arch. - Eur. J. Physiol. 454, 703–720 (2007).

    Article  CAS  Google Scholar 

  3. Hartenstein, V. & Posakony, J. W. Development 107, 389–405 (1989).

    Article  CAS  PubMed  Google Scholar 

  4. Hartenstein, V. & Posakony, J. W. Dev. Biol. 142, 13–30 (1990).

    Article  CAS  PubMed  Google Scholar 

  5. Ghysen, A., Dambly-Chaudière, C., Jan, L. Y. & Jan, Y. N. Genes Dev. 7, 723–733 (1993).

    Article  CAS  PubMed  Google Scholar 

  6. Rhyu, M. S., Jan, L. Y. & Jan, Y. N. Cell 76, 477–491 (1994).

    Article  CAS  PubMed  Google Scholar 

  7. Mangione, F. et al. Nat. Cell Biol. https://doi.org/10.1038/s41556-023-01110-2 (2023).

  8. Lee, J., Moon, S., Cha, Y. & Chung, Y. D. PLoS One 5, e11012 (2010).

    Article  PubMed  PubMed Central  Google Scholar 

  9. Liang, X., Madrid, J., Saleh, H. S. & Howard, J. Cytoskeleton 68, 1–7 (2011).

    Article  CAS  PubMed  Google Scholar 

  10. Zhang, W. et al. Cell 162, 1391–1403 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Woo, S.-H. et al. Nature 509, 622–626 (2014).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Woo, S.-H., Lumpkin, E. A. & Patapoutian, A. Trends Cell Biol. 25, 74–81 (2015).

    Article  PubMed  Google Scholar 

  13. Jenkins, B. A. & Lumpkin, E. A. Development 144, 4078–4090 (2017).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Keil, T. A. Microsc. Res. Tech. 39, 506–531 (1997).

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Physiology, UCSF/HHMI, San Francisco, CA, USA

    Ruijun Zhu & Yuh Nung Jan

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  1. Ruijun Zhu
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  2. Yuh Nung Jan
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Correspondence to Yuh Nung Jan.

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The authors declare no competing interests.

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Zhu, R., Jan, Y.N. A new cell in an old tactile sensory organ. Nat Cell Biol 25, 518–519 (2023). https://doi.org/10.1038/s41556-023-01119-7

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