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Mitochondrial efficiency directs cell fate

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Mitochondria are asymmetrically distributed to the daughter cells according to their age. A study now identifies metabolic features associated with mitochondrial age that regulate cell fate decisions.

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Fig. 1: Mitochondrial efficiency regulates cell fate.

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Correspondence to Jessica Brooke Spinelli or Elma Zaganjor.

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Spinelli, J.B., Zaganjor, E. Mitochondrial efficiency directs cell fate. Nat Cell Biol 24, 125–126 (2022). https://doi.org/10.1038/s41556-021-00834-3

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