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Challenges to making an egg

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Assembling egg cells involves cytoplasmic and nuclear processes that together enable embryonic development. A study now defines a set of transcription factors required for cytoplasmic, but not key nuclear, processes.

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Fig. 1: Diagrammatic representation of the generation of the female germ line from zygote formation through MII.

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Authors and Affiliations

  1. Department of Biology, University of Pennsylvania, Philadelphia, PA, USA

    Richard M. Schultz

  2. Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, CA, USA

    Richard M. Schultz

  3. The Jackson Laboratory, Bar Harbor, ME, USA

    John J. Eppig

Authors
  1. Richard M. Schultz
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  2. John J. Eppig
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Correspondence to Richard M. Schultz or John J. Eppig.

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The authors declare no competing interests

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Schultz, R.M., Eppig, J.J. Challenges to making an egg. Nat Cell Biol 23, 9–10 (2021). https://doi.org/10.1038/s41556-020-00622-5

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