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STEM CELLS

A fine balance in tendon healing

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Tendons have limited regenerative potential, and injuries often cause scarring. A study now identifies a tendon stem cell population that contributes to regeneration and a tendon fibro–adipogenic progenitor population involved in fibrosis.

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Fig. 1: A schematic of the two cell populations identified by Harvey et al. and their distinct roles in tendon healing.

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Authors and Affiliations

  1. Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, CA, USA

    Ashley L. Titan & Michael T. Longaker

  2. Hagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, CA, USA

    Ashley L. Titan & Michael T. Longaker

  3. Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA

    Michael T. Longaker

Authors
  1. Ashley L. Titan
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  2. Michael T. Longaker
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Correspondence to Michael T. Longaker.

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The authors declare no competing interests.

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Titan, A.L., Longaker, M.T. A fine balance in tendon healing. Nat Cell Biol 21, 1466–1467 (2019). https://doi.org/10.1038/s41556-019-0432-0

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