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Mechanopathology

Glycation-driven matrix crosslinking in cirrhosis

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Advanced glycation end products mediate the extensive crosslinking of the extracellular matrix in cirrhotic liver tissue.

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Fig. 1: Matrix crosslinking mediated by AGEs.

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Authors and Affiliations

  1. Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel

    Orit Kollet & Irit Sagi

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  1. Orit Kollet
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  2. Irit Sagi
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Correspondence to Irit Sagi.

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The authors declare no competing interests.

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Kollet, O., Sagi, I. Glycation-driven matrix crosslinking in cirrhosis. Nat. Biomed. Eng 7, 1343–1345 (2023). https://doi.org/10.1038/s41551-023-01119-w

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