Each of the 13 protein-coding genes in the mouse mitochondrial genome can be ablated using a library of optimized double-stranded-DNA deaminase-derived cytosine base editors.
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Lou, X., Shen, B. Ablating all mitochondrial protein-coding genes. Nat. Biomed. Eng 7, 609–611 (2023). https://doi.org/10.1038/s41551-022-00993-0
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DOI: https://doi.org/10.1038/s41551-022-00993-0
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