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Silicon biointerfaces for all scales

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Design principles for the development of silicon biointerfaces enable the non-genetic, light-controlled modulation of intracellular Ca2+ dynamics, and of cellular excitability in vitro, in tissue slices and in mouse brains.

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Fig. 1: Si-based biointerfaces enable optical control of cellular signalling at multiple scales.

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Authors and Affiliations

  1. Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA

    Seongjun Park, James A. Frank & Polina Anikeeva

  2. Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA

    Seongjun Park

  3. Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA

    Polina Anikeeva

Authors
  1. Seongjun Park
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  2. James A. Frank
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  3. Polina Anikeeva
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Correspondence to Polina Anikeeva.

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Park, S., Frank, J.A. & Anikeeva, P. Silicon biointerfaces for all scales. Nat Biomed Eng 2, 471–472 (2018). https://doi.org/10.1038/s41551-018-0268-0

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