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Systemic immune effects boost radiotherapy

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Nanoscale metal–organic frameworks carrying an immunotherapy payload and administered into tumours alongside a low dose of radiotherapy enhance local and systemic antitumour immunity in mouse models of breast cancer and colorectal cancer.

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Fig. 1: The combination of nanoscale metal–organic frameworks with radiotherapy and immunotherapy enhances local and systemic antitumour responses.

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Authors and Affiliations

  1. Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA

    Wilfred Ngwa

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  1. Wilfred Ngwa
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Correspondence to Wilfred Ngwa.

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Ngwa, W. Systemic immune effects boost radiotherapy. Nat Biomed Eng 2, 562–563 (2018). https://doi.org/10.1038/s41551-018-0264-4

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