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Making bone via nanoscale kicks

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Causing nanoscale vibrations in bone-marrow stromal cells embedded in a soft collagen gel induces the cells to undergo osteogenic differentiation and mineralization via mechanosensitive signalling pathways.

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Authors and Affiliations

  1. Biological Design Center, Department of Biomedical Engineering, Boston University, 610 Commonwealth Avenue, Boston, MA, 02215, USA

    Jeroen Eyckmans & Christopher S. Chen

  2. Wyss Institute for Biologically Inspired Engineering at Harvard University, 3 Blackfan Circle, Boston, MA, 02215, USA

    Jeroen Eyckmans & Christopher S. Chen

Authors
  1. Jeroen Eyckmans
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  2. Christopher S. Chen
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Correspondence to Jeroen Eyckmans or Christopher S. Chen.

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Eyckmans, J., Chen, C.S. Making bone via nanoscale kicks. Nat Biomed Eng 1, 689–690 (2017). https://doi.org/10.1038/s41551-017-0133-6

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