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A large family of stress-regulated SCOOP peptides and their processing by subtilases

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We reveal that a family of plant stress-induced signalling peptides, SERINE-RICH ENDOGENOUS PEPTIDES (SCOOPs), is much larger than originally thought, and identify key proteases required for their biogenesis. We find that impairing SCOOP biogenesis phenocopies a mutant of the SCOOP receptor MALE DISCOVERER 1-INTERACTING RECEPTOR-LIKE KINASE 2 (MIK2).

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Fig. 1: Subtilases are required to produce bioactive SCOOP peptides.

References

  1. Gully, K. et al. The SCOOP12 peptide regulates defense response and root elongation in Arabidopsis thaliana. J. Exp. Bot. 70, 1349–1365 (2019). A paper reporting the discovery of SCOOP peptides.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Rhodes, J. et al. Perception of a divergent family of phytocytokines by the Arabidopsis receptor kinase MIK2. Nat. Commun. https://doi.org/10.1038/s41467-021-20932-y (2021). A paper describing the identification of MIK2 as the SCOOP receptor.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Hou, S. et al. The Arabidopsis MIK2 receptor elicits immunity by sensing a conserved signature from phytocytokines and microbes. Nat. Commun. 12, 5494 (2021). A paper describing the identification of MIK2 as the SCOOP receptor.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Van der Does, D. et al. The Arabidopsis leucine-rich repeat receptor kinase MIK2/LRR-KISS connects cell wall integrity sensing, root growth and response to abiotic and biotic stresses. PLoS Genet. 13, e1006832 (2017). A paper describing the multiple functions of MIK2 in different stress responses.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Neukermans, J. et al. ARACINs, Brassicaceae-specific peptides exhibiting antifungal activities against necrotrophic pathogens in. Arabidopsis. Plant Physiol. 167, 1017–1029 (2015). A paper describing members of the SCOOP family as anti-microbial peptides.

    Article  CAS  PubMed  Google Scholar 

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This is a summary of: Yang, H. et al. Subtilase-mediated biogenesis of the expanded family of SERINE RICH ENDOGENOUS PEPTIDES. Nat. Plants https://doi.org/10.1038/s41477-023-01583-x (2023).

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A large family of stress-regulated SCOOP peptides and their processing by subtilases. Nat. Plants 9, 1954–1955 (2023). https://doi.org/10.1038/s41477-023-01584-w

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  • DOI: https://doi.org/10.1038/s41477-023-01584-w

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