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Plant resistosomes

Wheeling in a new era in plant immunity

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Pathogen perception in plants is mediated by immune receptors that detect specific pathogen molecules. Members of one diverse receptor family that occurs in all land plants form a structurally conserved activation complex with a shared signalling mechanism.

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Fig. 1: The activated resistosome complexes of Sr35 and ZAR1 share striking similarities in structure and function, as well as a conserved steric clash model mediating activation.

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Correspondence to Peter N. Dodds.

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Outram, M.A., Dodds, P.N. Wheeling in a new era in plant immunity. Nat. Plants 8, 1142–1143 (2022). https://doi.org/10.1038/s41477-022-01257-0

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