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Spotlight—author’s view for “Metabolic glycan labeling immobilizes dendritic cell membrane and enhances antitumorefficacy of dendritic cell vaccine”

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Fig. 1: Azido-sugars can be metabolized by DCs and become expressed on the cell membrane in the form of glycoproteins and glycolipids, which itself improves the activation status and antigen presentation ability of DCs.

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Acknowledgements

The authors would like to acknowledge the financial support from NSF DMR 2143673 CAR (HW), R01CA274738 (HW), R21CA270872 (HW), and the start-up package from the Department of Materials Science and Engineering at the University of Illinois at Urbana-Champaign and the Cancer Center at Illinois.

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Authors and Affiliations

  1. Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA

    Jiadiao Zhou & Hua Wang

  2. Cancer Center at Illinois (CCIL), Urbana, IL, 61801, USA

    Hua Wang

  3. Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA

    Hua Wang

  4. Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA

    Hua Wang

  5. Carle College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA

    Hua Wang

  6. Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA

    Hua Wang

  7. Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA

    Hua Wang

Authors
  1. Jiadiao Zhou
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  2. Hua Wang
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Contributions

JZ wrote the initial draft of the manuscript. HW revised the manuscript.

Corresponding author

Correspondence to Hua Wang.

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The authors declare no competing interests.

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Zhou, J., Wang, H. Spotlight—author’s view for “Metabolic glycan labeling immobilizes dendritic cell membrane and enhances antitumorefficacy of dendritic cell vaccine”. Genes Immun (2023). https://doi.org/10.1038/s41435-023-00245-4

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  • DOI: https://doi.org/10.1038/s41435-023-00245-4

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