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Delayed retroperitoneal liposarcoma diagnosis and management in a patient with massive obesity

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Abstract

People suffering from extreme obesity may be exposed to delayed diagnosis and treatment of cancer. A 37-year-old woman (weight = 245 kg, body mass index (BMI) = 79 kg/m2), presented a sepsis associated with nonspecific abdominal pain for 4 months. After several unsuccessful attempts due to her weight and a large waist circumference, abdominal CT scan was finally successfully performed and showed a large retroperitoneal mass. An ultrasound-guided core needle biopsy was performed and was in favor of a liposarcoma. Surgery was performed to remove the entire tumor of an estimated weight of 98 kg, a giant retroperitoneal dedifferentiated liposarcoma. This case highlights the difficulties to screen, diagnose, and manage cancers encountered in patients suffering from massive obesity.

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Fig. 1: Abdominal CT scan CT.
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References

  1. Group, the ESMO/European Sarcoma Network Working. Soft tissue and visceral sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018;0:iv1–7.

    Google Scholar 

  2. Bradley JC, Caplan R. Giant retroperitoneal sarcoma: a case report and review of the management of retroperitoneal liposarcoma. Am Surg. 2002;68:52–6.

    PubMed  Google Scholar 

  3. Maurice MJ, Yih JM, Ammori JB, Abouassaly R. Predictors of surgical quality for retroperitoneal sarcoma: volume matters. J Surg Oncol. 2017;116:766–74.

    Article  Google Scholar 

  4. MacNeill AJ, Gronchi A, Miceli R, Bonvalot S, Swallow CJ, Hohenberger P, et al. Postoperative morbidity after radical resection of primary retroperitoneal sarcoma: a report from the transatlantic RPS Working Group. Ann Surg. 2018;267:959–64.

    Article  Google Scholar 

  5. Stoeckle E, Ciondre JM, Bonvalot S, Kantor G, Terrier P, Bonichon F, et al. Prognostic factors in retroperitoneal sarcoma: a multivariate analysis of a series of 165 patients of the French Cancer Center Federation Sarcoma Group. Cancer. 2001;92:359–68.

    Article  CAS  Google Scholar 

  6. Said Basly M, Khouni H, Dridi M, Hellara W, Arbi EI, Kid HR, et al. Retroperitoneal liposarcoma. Tunis Med. 2009;87:552–4.

    PubMed  Google Scholar 

  7. Tan MCB, Brennan MF, Kuk D, Agaram NP, Antonescu CR, Qin L-X, et al. Histology-based classification predicts pattern of recurrence and improves risk stratification in primary retroperitoneal sarcoma. Ann Surg. 2016;263:593–600.

    Article  Google Scholar 

  8. Gronchi A, Strauss DC, Miceli R, Bonvalot S, Swallow CJ, Hohenberger P, et al. Variability in patterns of recurrence after resection of primary retroperitoneal sarcoma (RPS): a report on 1007 patients from the multi-institutional collaborative RPS Working Group. Ann Surg. 2016;263:1002–9.

    Article  Google Scholar 

  9. Messiou C, Morosi C. Imaging in retroperitoneal soft tissue sarcoma. J Surg Oncol. 2018;117:25–32.

    Article  Google Scholar 

  10. Cates JMM. Performance analysis of the american joint committee on cancer 8th edition staging system for retroperitoneal sarcoma and development of a new staging algorithm for sarcoma-specific survival. Ann Surg Oncol. 2017;24:3880–7.

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. AP-HP-centre, Service de Nutrition, Centre Spécialisé Obésité, Hôpital européen Georges-Pompidou, Paris, France

    Claire Rives-Lange, Amel Ait Boudaoud, Charles Barsamian, Alina Radu, Jean-François Perregaux, Claire Carette & Sébastien Czernichow

  2. Université de Paris, Paris, France

    Claire Rives-Lange, Tigran Poghosyan, Charles Dariane, Richard Douard, Amel Ait Boudaoud, Frédérique Larousserie, Claire Carette & Sébastien Czernichow

  3. INSERM, UMR1153, Epidemiology and Biostatistics Sorbonne Paris Cité Center (CRESS), METHODS team, Paris, France

    Claire Rives-Lange & Sébastien Czernichow

  4. AP-HP-centre, Service de chirurgie digestive, Hôpital Européen Georges Pompidou, Paris, France

    Tigran Poghosyan & Richard Douard

  5. AP-HP-centre, Service d’urologie, Hôpital Européen Georges Pompidou, Paris, France

    Charles Dariane

  6. Service d’endocrinologie, Centre hospitalier régional d’Orléans, Orléans, France

    Elise Mongeois

  7. AP-HP-centre, Service d’anatomie pathologique, Hôpital Européen Georges Pompidou, Paris, France

    Christine Lagorce & Virginie Verkarre

  8. AP-HP-centre, Service de Pathologie, Hôpital Cochin, Paris, France

    Frédérique Larousserie

  9. AP-HP-Nord, service d’hepato-gastro-enterologie, Hôpital Beaujon, Clichy, France

    Fransisca Joly

Authors
  1. Claire Rives-Lange
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  2. Tigran Poghosyan
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  3. Charles Dariane
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  4. Richard Douard
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  5. Elise Mongeois
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  6. Amel Ait Boudaoud
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  7. Charles Barsamian
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  8. Alina Radu
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  9. Christine Lagorce
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  10. Virginie Verkarre
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  11. Frédérique Larousserie
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  12. Jean-François Perregaux
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  13. Fransisca Joly
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  14. Claire Carette
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  15. Sébastien Czernichow
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Corresponding author

Correspondence to Claire Rives-Lange.

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Rives-Lange, C., Poghosyan, T., Dariane, C. et al. Delayed retroperitoneal liposarcoma diagnosis and management in a patient with massive obesity. Eur J Clin Nutr 75, 1520–1522 (2021). https://doi.org/10.1038/s41430-020-00855-5

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  • DOI: https://doi.org/10.1038/s41430-020-00855-5

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