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At the end, remodeling leads to eviction

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The induction and repair of chromosome breaks is associated with myriad changes in chromatin. A recent study shows that chromatin remodeling that results in histone eviction at the break site requires the Mre11 complex and INO80 and that these events are important for efficient loading of the Rad51 recombinase.

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Authors and Affiliations

  1. Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, 10021, New York, USA

    John H J Petrini

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  1. John H J Petrini
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Petrini, J. At the end, remodeling leads to eviction. Nat Struct Mol Biol 12, 1028–1029 (2005). https://doi.org/10.1038/nsmb1205-1028

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