Bacteria sequester key metabolic steps into polyhedral protein compartments. A newly discovered nanocompartment reveals what it takes for its cargo protein to become encapsulated within a protein shell.
References
Shively, J.M. (ed.) Inclusions in Prokaryotes (Springer, Berlin:Heidelberg, 2006).
Shively, J.M. (ed.) Complex Intracellular Structures in Prokaryotes (Springer, Berlin:Heidelberg, 2006).
Heinhorst, S., Cannon, G.C. & Shively, J.M. Carboxysomes and carboxysome-like inclusions. in Complex Intracellular Structures in Prokaryotes Vol. 2 (ed. Shively, J.M.) 141–164 (Springer, Berlin:Heidelberg, 2006).
Sriramulu, D.D. et al. J. Bacteriol. 190, 4559–4567 (2008).
Bobik, T.A. Appl. Microbiol. Biotechnol. 70, 517–525 (2006).
Kerfeld, C.A. et al. Science 309, 936–938 (2005).
Tsai, Y. et al. PLoS Biol. 5, e144 (2007).
Tanaka, S. et al. Science 319, 1083–1086 (2008).
Sutter, M. et al. Nat. Struct. Mol. Biol. 15, 939–947 (2008).
Valdes-Stauber, N. & Scherer, S. Appl. Environ. Microbiol. 60, 3809–3814 (1994).
Rosenkrands, I. et al. Infect. Immun. 66, 2728–2735 (1998).
Hicks, P.M., Rinker, K.D., Baker, J.R. & Kelly, R.M. FEBS Lett. 440, 393–398 (1998).
Akita, F. et al. J. Mol. Biol. 368, 1469–1483 (2007).
Nelson, K.E. et al. 399, 323–329 (1999).
Badger, M.R. & Bek, E.J. J. Exp. Bot. 59, 1525–1541 (2008).
Yeates, T.O., Kerfeld, C.A., Heinhorst, S., Cannon, G.C. & Shively, J.M. Nat. Rev. Microbiol. 6, 681–691 (2008).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Heinhorst, S., Cannon, G. A new, leaner and meaner bacterial organelle. Nat Struct Mol Biol 15, 897–898 (2008). https://doi.org/10.1038/nsmb0908-897
Issue Date:
DOI: https://doi.org/10.1038/nsmb0908-897
- Springer Nature America, Inc.
This article is cited by
-
Bacterial encapsulins as orthogonal compartments for mammalian cell engineering
Nature Communications (2018)