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Spliceosome assembly in yeast: one ChIP at a time?

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When and how the spliceosome assembles on its substrates in living yeast cells has been unclear. It is now evident that the 'when' is during transcription; the 'how' remains debatable.

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Figure 1: Nascent RNA ChIP.

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Authors and Affiliations

  1. the Center for RNA Molecular Biology, Case Western Reserve University School of Medicine, 10900 Euclid Avenue, Cleveland, 44106-4973, Ohio, USA

    Timothy W Nilsen

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  1. Timothy W Nilsen
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Nilsen, T. Spliceosome assembly in yeast: one ChIP at a time?. Nat Struct Mol Biol 12, 571–573 (2005). https://doi.org/10.1038/nsmb0705-571

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