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How HIV-1 hijacks ALIX

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Two new crystal structures shed light on how a component of the endosomal budding machinery is co-opted by human immunodeficiency virus-1 to facilitate virus budding from the cell surface.

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Figure 1: Domain organization and structure of ALIX.

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Authors and Affiliations

  1. Heinrich G. Göttlinger is in the Program in Gene Function and Expression, Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA. heinrich.gottlinger@umassmed.edu,

    Heinrich G Göttlinger

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  1. Heinrich G Göttlinger
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Göttlinger, H. How HIV-1 hijacks ALIX. Nat Struct Mol Biol 14, 254–256 (2007). https://doi.org/10.1038/nsmb0407-254

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