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Enforcing silencing: dynamic HP1 complexes in Neurospora

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Abstract

Analysis of the Neurospora crassa chromodomain protein CDP-2, a component of a newly characterized HP1-containing complex, reveals a second gene-silencing mechanism and provides insights into the dynamic nature of chromatin domains that possess shared components.

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Figure 1: Diagram of the dynamic changes among chromatin domains possessing shared factors in different genetic backgrounds.

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Authors and Affiliations

  1. Lori L. Wallrath is in the Department of Biochemistry, University of Iowa, Iowa City, Iowa, USA.,

    Lori L Wallrath

  2. Sarah C. R. Elgin is in the Department of Biology, Washington University, St. Louis, Missouri, USA.,

    Sarah C R Elgin

Authors
  1. Lori L Wallrath
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  2. Sarah C R Elgin
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Corresponding author

Correspondence to Sarah C R Elgin.

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The authors declare no competing financial interests.

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Wallrath, L., Elgin, S. Enforcing silencing: dynamic HP1 complexes in Neurospora. Nat Struct Mol Biol 19, 465–467 (2012). https://doi.org/10.1038/nsmb.2291

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