New structural analysis finds a metal-oxo clusters bound to the iron trafficking protein Fbp. Does this point to a possible strategy for bacterial iron acquisition?
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Figure courtesy of Peter Allen.
References
Alexeev, D. et al. Nat. Struct. Biol. 10, 297–302 (2003).
Lankford, C.E. CRC Crit. Rev. Microbiol. 2, 273–331 (1973).
Ferreiros, C., Criado, M.T., & Gomez, J.A. Comp. Biochem. Physiol. B, 123, 1–7 (1999).
Aisen, P. in Metal Ions in Biological Systems Vol. 35 (eds. Sigel, A. and Sigel, H.) 585–631 (Marcel Dekker, New York; 1998).
Taboy, C.H., Vaughan, K.G., Mietzner, T.A., Aisen, P. & Crumblis, A.L. J. Biol. Chem. 176, 2719–2714 (2001).
Ledyard, K.M. & Butler, A. J. Biol. Inorg. Chem., 2, 93–97 (1997).
Heidelberg, J.F. et al. Nat. Biotechnol. 20, 1118–1123 (2002).
Lower, S.K., Hochella, M.F. Jr. & Beveridge, T.J. Science 292, 1360–1363 (2001).
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Butler, A. Iron acquisition: straight up and on the rocks?. Nat Struct Mol Biol 10, 240–241 (2003). https://doi.org/10.1038/nsb0403-240
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DOI: https://doi.org/10.1038/nsb0403-240
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