Skip to main content
SpringerLink
Log in

Chemogenetics

  • News & Views
  • Published:

From Nature Structural Biology

View current issue Submit your manuscript

High-resolution structure analysis and directed mutagenesis experiments may at last be brought into step by the use of functional group analogues that alter individual atoms

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Smith, S.A., Sharanabasava, B.R. and McLaughlin, L.W. Nature struct. Biol. 1, 23–29 (1994).

    Article  Google Scholar 

  2. Otwinowski, Z., Schevitz, R.W., Zhang, R.-G., Lawson, C.L., Joachimiak, A., Marmorstein, R.Q., Luisi, F.B. and Sigler, P B. Nature 335, 321–329 (1988).

    Article  CAS  Google Scholar 

  3. Mazzarelli, J.M., Rajur, S.B., Iadorola, P.L. and McLaughlin, L.W. Biochemistry 31, 5925–5936 (1992).

    Article  CAS  Google Scholar 

  4. Aiken, C.R. and Gumport, R.L. Meth. Enzym. 208, 433–457 (1991).

    Article  CAS  Google Scholar 

  5. Starr, D.B. and Hawley, D.K. Cell 67, 1231–1240 (1991).

    Article  CAS  Google Scholar 

  6. Lesser, D.R., Kurpiewski, M.R., Waters, T., Connolly, B.A. and Jen-Jacobson, L. Proc. natn. Acad. Sci. U.S.A. 90, 7548–7552 (1993).

    Article  CAS  Google Scholar 

  7. Staacke, D., Walter, B., Kisters-Wolke, B., Wiicken-Bergman and Muller-Hill, B. EMBO J. 9, 1963–1967 (1990).

    Article  CAS  Google Scholar 

  8. Haran, T.E., Joachimiak, A. and Sigler, P.B. EMBO J. 11, 3021–3030 (1992).

    Article  CAS  Google Scholar 

  9. Carey, J.D., Lewis, E.A., Lavole, T.A. and Yang, J. J. biol. Chem. 266, 24509–24513 (1991).

    CAS  PubMed  Google Scholar 

  10. Lawson, C.L. and Carey, J. Nature 366, 178–182 (1993).

    Article  CAS  Google Scholar 

  11. Ellman, J., Mendell, D., Anthony-Cahill, S., Noren, C.J. and Schultz, P.G. Meth. Enzym. 202, 301–336 (1991).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Dept of Molecular Biophysics and Biochemistry and The Howard Hughs Medical Institute, Yale Universty, Room 154, 295 Congress Avenue, New Haven, Connecticut, 06510, USA

    Paul B. Sigler

Authors
  1. Paul B. Sigler
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sigler, P. Chemogenetics. Nat Struct Mol Biol 1, 3–4 (1994). https://doi.org/10.1038/nsb0194-3

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nsb0194-3

  • Springer Nature America, Inc.

Search

Navigation