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Systemic sclerosis in 2016

Dermal white adipose tissue implicated in SSc pathogenesis

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From Nature Reviews Rheumatology

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Several strands of new research indicate that skin-specific adipocyte progenitor cells regulate myofibroblasts and skin fibrosis in scleroderma.

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Figure 1: Loss of dermal white adipose tissue in systemic sclerosis (SSc).

References

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Authors and Affiliations

  1. Division of Rheumatology and Northwestern Scleroderma Program, Northwestern University Feinberg School of Medicine, 240 East Huron Street, Chicago, 60657, Illinois, USA

    John Varga & Roberta G. Marangoni

Authors
  1. John Varga
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  2. Roberta G. Marangoni
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Correspondence to John Varga.

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The authors declare no competing financial interests.

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Varga, J., Marangoni, R. Dermal white adipose tissue implicated in SSc pathogenesis. Nat Rev Rheumatol 13, 71–72 (2017). https://doi.org/10.1038/nrrheum.2016.223

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