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Rheumatoid arthritis

Disconnect in the effects of obesity on RA outcomes

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Obesity in rheumatoid arthritis is characterized by high disease activity and low rates of remission; paradoxically, it is also associated with reduced radiographic progression. So, is intentional weight loss beneficial or detrimental to articular outcomes?

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Figure 1: Effect of obesity on rheumatoid arthritis outcomes: disconnect between subjective disease activity and radiographic progression.

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Authors and Affiliations

  1. Rheumatology Department, Sorbonnes Universités UPMC Univ Paris 06, INSERM UMRS_938, DHU i2B

    Alice Courties & Jérémie Sellam

  2. Assistance Publique-Hopitaux de Paris (AP-HP) Hôpital Saint-Antoine, 184 rue du Faubourg Saint-Antoine, Paris, 75012, France

    Alice Courties & Jérémie Sellam

Authors
  1. Alice Courties
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  2. Jérémie Sellam
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Correspondence to Jérémie Sellam.

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The authors declare no competing financial interests.

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Courties, A., Sellam, J. Disconnect in the effects of obesity on RA outcomes. Nat Rev Rheumatol 12, 501–502 (2016). https://doi.org/10.1038/nrrheum.2016.121

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