Radiographic joint-space width is the standard structural outcome for trials in knee osteoarthritis (OA), but MRI provides comprehensive 3D insights into the multi-tissue pathology of OA and could provide a superior means of monitoring disease progression and response to treatment. A new study highlights bone as an imaging biomarker.
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Acknowledgements
This work was supported by NIH grant AR47785 (to T.N. and D.T.F.) and an Arthritis Foundation Innovative Research Grant (to T.N.).
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Neogi, T., Felson, D. Bone as an imaging biomarker and treatment target in OA. Nat Rev Rheumatol 12, 503–504 (2016). https://doi.org/10.1038/nrrheum.2016.113
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DOI: https://doi.org/10.1038/nrrheum.2016.113
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