Skip to main content

Advertisement

Log in

Therapy

Optimized treatment algorithms for digital vasculopathy in SSc

  • News & Views
  • Published:

From Nature Reviews Rheumatology

View current issue Sign up to alerts

Early identification of secondary Raynaud phenomenon is essential to treat the underlying disease—most frequently systemic sclerosis (SSc). Integrated therapeutic approaches and monitoring systems that offer improved modalities of care feature in the new best practice recommendations for the treatment of digital vasculopathy in SSc.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Integrated treatment recommendations for primary and secondary Raynaud phenomenon in patients with SSc.

References

  1. Hughes, M. et al. Consensus best practice pathway of the UK Systemic Sclerosis Study Group: digital vasculopathy in systemic sclerosis. Rheumatology (Oxford) http://dx.doi.org/10.1093/rheumatology/kev201.

  2. Garner, R., Kumari, R., Lanyon, P., Doherty, M. & Zhang, W. Epidemiology prevalence, risk factors and associations of primary Raynaud's phenomenon: systematic review and meta-analysis of observational studies. BMJ Open 5, e006389 (2015).

    Article  Google Scholar 

  3. Nietert, P. J. et al. Raynaud phenomenon and mortality: 20+ years of follow-up of the Charleston Heart Study cohort. Clin. Epidemiol. 7, 161–168 (2015).

    Article  Google Scholar 

  4. Cutolo, M., Pizzorni, C. & Sulli, A. Identification of transition from primary Raynaud's phenomenon to secondary Raynaud's phenomenon by nailfold videocapillaroscopy : comment on the article by Hirschl et al. Arthritis Rheum. 56, 2102–2103 (2007).

    Article  Google Scholar 

  5. Cutolo, M., Sulli, A. & Smith, V. Assessing microvascular changes in systemic sclerosis diagnosis and management. Nat. Rev. Rheumatol. 6, 578–587 (2010).

    Article  Google Scholar 

  6. Smith, V. et al. Nailfold capillaroscopy for prediction of novel future severe organ involvement in systemic sclerosis. J. Rheumatol. 40, 2023–2028 (2013).

    Article  Google Scholar 

  7. Cutolo, M. Disease modification in systemic sclerosis. Do integrated approaches offer new challenges? Z. Rheumatol. 72, 326–328 (2013).

    Article  CAS  Google Scholar 

  8. Avouac, J. & Allanore, Y. Targeted immunotherapies in systemic sclerosis. Clin. Exp. Rheumatol. 32 (2 Suppl. 81), 165–172 (2014).

    PubMed  Google Scholar 

  9. Korn, J. H. et al. Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist. Arthritis Rheum. 50, 3985–3993 (2004).

    Article  CAS  Google Scholar 

  10. Cutolo, M. et al. Longterm treatment with endothelin receptor antagonist bosentan and iloprost improves fingertip blood perfusion in systemic sclerosis. J. Rheumatol. 41, 881–886 (2014).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Maurizio Cutolo.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

PowerPoint slides

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Cutolo, M., Sulli, A. Optimized treatment algorithms for digital vasculopathy in SSc. Nat Rev Rheumatol 11, 569–571 (2015). https://doi.org/10.1038/nrrheum.2015.111

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrrheum.2015.111

  • Springer Nature Limited

This article is cited by

Navigation