Skip to main content
Log in

Crystal arthritis

Calcium pyrophosphate deposition—nothing 'pseudo' about it!

  • News & Views
  • Published:

From Nature Reviews Rheumatology

View current issue Sign up to alerts

Calcium pyrophosphate disease remains—50 years after its initial description—a challenging disease to diagnose and manage. Newly-reached consensus among European experts suggests standard nomenclature, some recommendations for diagnosis and treatment, and an ambitious future research agenda based on these decisions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. McCarty, D. J. Jr, Kohn, N. N. & Faires, J. S. The significance of calcium pyrophosphate crystals in the synovial fluid of arthritic patients: the “pseudogout syndrome”. I. Clinical aspects. Ann. Intern. Med. 56, 711–737 (1962).

    Article  CAS  Google Scholar 

  2. Žitňan, D. & Sit'Aj, Š. Chondrocalcinosis articularis. Section I. Clinical and radiological study. Ann. Rheum. Dis. 22, 142–152 (1963).

    Article  Google Scholar 

  3. Fuerst, M. et al. Calcification of articular cartilage in human osteoarthritis. Arthritis Rheum. 60, 2694–2703 (2009).

    Article  CAS  Google Scholar 

  4. Zhang, W. et al. European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis. Ann. Rheum. Dis. 70, 563–570 (2011).

    Article  CAS  Google Scholar 

  5. Zhang, W. et al. EULAR recommendations for calcium pyrophosphate deposition. Part II: management. Ann. Rheum. Dis. 70, 571–575 (2011).

    Article  CAS  Google Scholar 

  6. Dieppe, P. & Swan, A. Identification of crystals in synovial fluid. Ann. Rheum. Dis. 58, 261–263 (1999).

    Article  CAS  Google Scholar 

  7. von Essen, R., Hölttä, A. M. & Pikkarainen, R. Quality control of synovial fluid crystal identification. Ann. Rheum. Dis. 57, 107–109 (1998).

    Article  CAS  Google Scholar 

  8. Das, S. K. et al. A randomized controlled trial to evaluate the slow-acting symptom modifying effects of a regimen containing colchicine in a subset of patients with osteoarthritis of the knee. Osteoarthritis Cartilage 10, 247–252 (2002).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ann K. Rosenthal.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rosenthal, A., Ryan, L. Calcium pyrophosphate deposition—nothing 'pseudo' about it!. Nat Rev Rheumatol 7, 257–258 (2011). https://doi.org/10.1038/nrrheum.2011.50

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrrheum.2011.50

  • Springer Nature Limited

Navigation