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Neuro-oncology

In search of molecular markers of glioma in elderly patients

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Elderly patients represent a growing proportion of individuals with malignant glioma, but are often excluded from trials owing to their poor prognosis. In a new study, researchers have investigated molecular markers of glioma specifically in elderly patients—are these markers of clinical use?

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Figure 1: Pathogenetic and epigenetic evolution of glioma in adults.

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Acknowledgements

This work has been supported by the Swiss National Science Foundation, the Swiss Cancer League, and the Swiss Bridge Award 2011.

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Correspondence to Roger Stupp.

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The authors declare no competing financial interests.

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Hegi, M., Stupp, R. In search of molecular markers of glioma in elderly patients. Nat Rev Neurol 9, 424–425 (2013). https://doi.org/10.1038/nrneurol.2013.127

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