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Parkinson disease

Serotonin reuptake inhibitors for depression in PD

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A recent study to investigate the safety and efficacy of serotonin reuptake inhibitors suggests that these drugs are beneficial for the treatment of depressive disorders in Parkinson disease. Whether these treatments will offer such benefits in the long term compared with other pharmacological and nonpharmacological approaches remains to be determined.

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Authors and Affiliations

  1. Department of Clinical Pharmacology and Neuroscience, University Hospital, University of Toulouse III, Toulouse, France

    Santiago Perez-Lloret & Olivier Rascol

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  1. Santiago Perez-Lloret
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  2. Olivier Rascol
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Correspondence to Olivier Rascol.

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Competing interests

O. Rascol has acted as a scientific advisor for Boehringer-Ingelheim in the development of antiparkinsonian medications. He has received unrestricted scientific grants from Novartis, Boehringer-Ingelheim, Eisai, Euthérapie, Faust Pharmaceuticlas, GlaxoSmithKline, Lundbeck, Solvay, and TEVA. S. Perez-Lloret declares no competing interests.

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Perez-Lloret, S., Rascol, O. Serotonin reuptake inhibitors for depression in PD. Nat Rev Neurol 8, 365–366 (2012). https://doi.org/10.1038/nrneurol.2012.111

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