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Parkinson disease

Parkinson disease clinical subtypes and their implications

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Despite the emergence of genetic and molecular approaches, disease categorization on the basis of clinical features remains an appealing approach, especially where the molecular mechanisms are poorly understood. A new study supports distinct clinical subtypes of Parkinson disease that could have implications for understanding the etiology of this condition.

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Figure 1: Biochemical senescence and pathogenetic pathways to cell death in Parkinson disease.

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Authors and Affiliations

  1. Department of Clinical Neurosciences, University College London Institute of Neurology, Rowland Hill Street, NW3 2PF, London, UK

    Anthony H. V. Schapira & Anette Schrag

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  1. Anthony H. V. Schapira
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  2. Anette Schrag
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Correspondence to Anthony H. V. Schapira.

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The authors declare no competing financial interests.

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Schapira, A., Schrag, A. Parkinson disease clinical subtypes and their implications. Nat Rev Neurol 7, 247–248 (2011). https://doi.org/10.1038/nrneurol.2011.40

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