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Dementia in 2010

Paving the way for Alzheimer disease drug development

  • Year in Review
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From Nature Reviews Neurology

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Advances in Alzheimer disease (AD) research during 2010 have identified promising novel diagnostic tools and therapeutic targets for this condition, and suggest that amyloid-β immunotherapy reduces plaque load in patients with AD. A new lexicon for AD has also been proposed.

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Figure 1: Timeline of clinical definitions and criteria and developments in diagnostic biomarkers for AD.

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Authors and Affiliations

  1. Department of Psychiatry and Neurochemistry, Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Göteborgsvägen 31, SE-431 80, Mölndal, Sweden

    Kaj Blennow

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  1. Kaj Blennow
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Competing interests

K. Blennow has received honoraria from Janssen Alzheimer Immunotherapy.

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Blennow, K. Paving the way for Alzheimer disease drug development. Nat Rev Neurol 7, 65–66 (2011). https://doi.org/10.1038/nrneurol.2010.214

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  • DOI: https://doi.org/10.1038/nrneurol.2010.214

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