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Neurodegenerative disease

Diabetes, microvascular pathology and Alzheimer disease

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Epidemiological studies suggest that the risk of developing cognitive impairment and dementia is increased in individuals with diabetes mellitus, although the evidence from clinicopathological studies on neurodegenerative changes is at odds with these observations. A thorough appraisal of concomitant vascular changes in dementia might resolve this incongruity.

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  1. R. N. Kalaria, Institute for Ageing and Health, Wolfson Research Center (Neuropathology), Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 5PL, UK r.n.kalaria@ncl.ac.uk

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  1. Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK

    Raj N. Kalaria

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  1. Raj N. Kalaria
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The author declares no competing financial interests.

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Kalaria, R. Diabetes, microvascular pathology and Alzheimer disease. Nat Rev Neurol 5, 305–306 (2009). https://doi.org/10.1038/nrneurol.2009.72

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