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Hypertension

Renal denervation—promising data from the DENERHTN trial

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In patients with resistant hypertension, renal denervation plus standardized stepped-care antihypertensive treatment (SSAHT) resulted in significant blood-pressure lowering compared with SSAHT alone. These new data from the DENERHTN trial may indicate that despite the failure of SYMPLICITY HTN-3, there is light at the end of the tunnel for renal denervation.

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References

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Acknowledgements

The authors are grateful to the investigators of the European Network Coordinating Research on Renal Denervation, who substantially contributed to the insights expressed in this commentary. They are especially indebted to Y. Jin (University of Leuven, Belgium), F. E. M. Fadl Elmula and S. E. Kjeldsen (both University of Oslo, Norway).

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Authors and Affiliations

  1. KU Leuven Department of Cardiovascular Sciences, Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, University of Leuven, Kapucijnenvoer 35, Box 7001, Leuven, BE-3000, Belgium

    Wen-Yi Yang & Jan A. Staessen

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  1. Wen-Yi Yang
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  2. Jan A. Staessen
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Correspondence to Jan A. Staessen.

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The authors declare no competing financial interests.

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Yang, WY., Staessen, J. Renal denervation—promising data from the DENERHTN trial. Nat Rev Nephrol 11, 258–260 (2015). https://doi.org/10.1038/nrneph.2015.28

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