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Should we use fibrates in patients with diabetes and mild CKD?

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Recent analyses from the FIELD randomized trial of fenofibrate in type 2 diabetes mellitus suggests that fibrates have beneficial effects and are safe in patients with moderate renal impairment. However, too few participants with chronic kidney disease were included in the study to provide reliable information.

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Authors and Affiliations

  1. University of Oxford, Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Richard Doll Building, Old Road Campus, Roosevelt Drive, OX3 7LF, Oxford, UK

    David Lewis

  2. Department of Medicine I, Division of Nephrology, University Hospital, Oberdürrbacher Strasse 6, 97080, Würzburg, Germany

    Christoph Wanner

Authors
  1. David Lewis
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  2. Christoph Wanner
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Correspondence to Christoph Wanner.

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The authors declare no competing financial interests.

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Lewis, D., Wanner, C. Should we use fibrates in patients with diabetes and mild CKD?. Nat Rev Nephrol 8, 201–202 (2012). https://doi.org/10.1038/nrneph.2012.37

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