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Acute kidney injury

Fluid therapy in acute kidney injury: the FACTTs

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The consequences of fluid administration and the maintenance of fluid balance, despite their ubiquity in critical care, remain a topic of much debate among clinicians. Emerging evidence suggests that fluid administration and a positive fluid balance can be harmful in a number of conditions, including acute kidney injury.

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Figure 1: Comparison of mean daily furosemide dose and fluid balance between survivors and nonsurvivors in Grams et al.'s study.

References

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Authors and Affiliations

  1. Department of Intensive Care, Austin Hospital, 147 Studley Road, Heidelberg, Melbourne, 3084, VIC, Australia

    Neil J. Glassford

  2. Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, 89 Commercial Road, Melbourne, 3004, VIC, Australia

    Rinaldo Bellomo

Authors
  1. Neil J. Glassford
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  2. Rinaldo Bellomo
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Correspondence to Rinaldo Bellomo.

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The authors declare no competing financial interests.

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Glassford, N., Bellomo, R. Fluid therapy in acute kidney injury: the FACTTs. Nat Rev Nephrol 7, 305–306 (2011). https://doi.org/10.1038/nrneph.2011.57

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