Skip to main content
SpringerLink
Log in

Sequencing the species pan-genome

  • Genome Watch
  • Published:

From Nature Reviews Microbiology

View current issue Sign up to alerts

Abstract

This month's Genome Watch discusses the recent advances in sequencing technology that have allowed microbiologists to determine the genome sequences not just of individual species but also of entire genera and have allowed a view of the entire pan-bacterial genome.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: The bacterial pan-genome.

References

  1. Lapierre, P. & Gogarten, J. P. Estimating the size of the bacterial pan-genome. Trends Genet. 23 Jan 2009 (doi: 10.1016/j.tig.2008.12.004).

    Article  CAS  PubMed  Google Scholar 

  2. Tettelin, H. et al. Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial “pan-genome”. Proc. Natl Acad. Sci. USA 102, 13950–13955 (2005).

    Article  CAS  PubMed  Google Scholar 

  3. Hiller, N. L. et al. Comparative genomic analyses of seventeen Streptococcus pneumoniae strains: insights into the pneumococcal supragenome. J. Bacteriol. 189, 8186–8195 (2007).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Bentley, S. D. et al. Genetic analysis of the capsular biosynthetic locus from all 90 pneumococcal serotypes. PLoS Genet. 2, e31 (2006).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Lefébure, T. & Stanhope, M. J. Evolution of the core and pan-genome of Streptococcus: positive selection, recombination, and genome composition. Genome Biol. 8, R71 (2007).

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Stephen Bentley is at the Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. microbes@sanger.ac.uk,

    Stephen Bentley

Authors
  1. Stephen Bentley
    View author publications

    You can also search for this author in PubMed Google Scholar

Related links

Related links

DATABASES

Entrez Genome Project

Bacillus anthracis

Bacillus cereus

Streptococcus agalactiae

Streptococcus pneumoniae

Streptococcus pyogenes

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bentley, S. Sequencing the species pan-genome. Nat Rev Microbiol 7, 258–259 (2009). https://doi.org/10.1038/nrmicro2123

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrmicro2123

  • Springer Nature Limited

This article is cited by

Search

Navigation