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Let the data speak

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Figure 1: A comparison of phases between sets of the most periodic genes as determined by Fourier analysis (P-value <0.001, 112 genes plotted).
Figure 2: A direct comparison of individual transcript profiles between the long-period and short-period expression data sets.

References

  1. Tu, B. P., Kudlicki, A., Rowicka, M. & McKnight, S. L. Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes. Science 310, 1152–1158 (2005).

    Article  CAS  Google Scholar 

  2. Klevecz, R. R., Bolen, J., Forrest, G. & Murray, D. B. A genomewide oscillation in transcription gates DNA replication and cell cycle. Proc. Natl Acad. Sci. USA 101, 1200–1205 (2004).

    Article  CAS  Google Scholar 

  3. Adams, C. A., Kuriyama, H., Lloyd, D. & Murray, D. B. The Gts1 protein stabilizes the autonomous oscillator in yeast. Yeast 20, 463–470 (2003).

    Article  CAS  Google Scholar 

  4. Tu, B. P. & McKnight, S. L. Metabolic cycles as an underlying basis of biological oscillations. Nature Rev. Mol. Cell Biol. 7, 696–701 (2006).

    Article  CAS  Google Scholar 

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Correspondence to Steven L. McKnight.

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Tu, B., Kudlicki, A., Rowicka, M. et al. Let the data speak. Nat Rev Mol Cell Biol 7, 1–2 (2006). https://doi.org/10.1038/nrm1980-c3

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