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Why does immunity to parasites take so long to develop?

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Abstract

To ensure successful transmission and establish chronic infection, parasites must evade the host's immune system and delay the development of immunity. Maria Yazdanbakhsh and David Sacks discuss how this might be achieved.

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Author information

Authors and Affiliations

  1. Maria Yazdanbakhsh is at the Department of Parasitology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, The Netherlands.,

    Maria Yazdanbakhsh

  2. David L. Sacks is at the Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.,

    David L. Sacks

Authors
  1. Maria Yazdanbakhsh
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  2. David L. Sacks
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Corresponding author

Correspondence to David L. Sacks.

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Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary information S1 (Table)

Global impact of parasitic diseases', and current control measures (PDF 125 kb)

Supplementary information S2 (Figure)

Evading immune elimination. (PDF 525 kb)

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Yazdanbakhsh, M., Sacks, D. Why does immunity to parasites take so long to develop?. Nat Rev Immunol 10, 80–81 (2010). https://doi.org/10.1038/nri2673

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