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Decision making during the conception and career of CD4+ T cells

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From Nature Reviews Immunology

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Abstract

The mechanisms by which thymocytes commit to becoming CD4+ T cells and how these cells subsequently can adopt various cell fates are becoming important paradigms of developmental programming. Understanding how such CD4+ T-cell diversity accommodates both immune reaction against various challenges and the suppression of undesirable responses is also revealing new therapeutic options.

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Authors and Affiliations

  1. Abramson Family Cancer Research Institute and Department of Medicine, Division of Infectious Diseases, University of Pennsylvania, Philadelphia, 19104–6160, Pennsylvania, USA

    Steven L. Reiner

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  1. Steven L. Reiner
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Reiner, S. Decision making during the conception and career of CD4+ T cells. Nat Rev Immunol 9, 81–82 (2009). https://doi.org/10.1038/nri2490

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  • DOI: https://doi.org/10.1038/nri2490

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