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Gut microbiota

Changes in gut microbes and host metabolism: squaring the circle?

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From Nature Reviews Gastroenterology & Hepatology

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Converging studies have shown that the gut microbiota composition and activity possibly contribute to shape host metabolism. A new study deeply analysed metabolic parameters in humans with obesity after short-term antibiotic exposure; the conclusion calls into doubt some direct and simple associations found between the gut microbiota and metabolic disorders

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Figure 1: Hypothetical interactions between gut microbiota and host health.

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Acknowledgements

P.D.C. is a research associate at Fonds de la Recherche Scientifique (FRS-FNRS) and the recipient of grants from FNRS (convention J.0084.15, convention 3.4579.11), Projet de Recherche convention: T.0138.14 and Walloon region DG06-FSO project (Microbes 1510053). This work was supported by the FRFS-WELBIO under grant: WELBIO-CR-2012S-02R. This work is also supported in part by the Funds Baillet Latour (Grant for Medical Research 2015). P.D.C. is a recipient of a European Research Council (ERC) Proof of Concept grant 2016 (Microbes4U_713547) and an ERC Starting Grant 2013 (Starting grant 336452-ENIGMO).

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  1. Université Catholique de Louvain, Louvain Drug Research Institute, Walloon Excellence in Life sciences and Biotechnology (WELBIO), Metabolism and Nutrition research group, Avenue Emmanuel Mounier, 73 Box B1.73.11, Brussels, B-1200, Belgium

    Patrice D. Cani

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Correspondence to Patrice D. Cani.

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Cani, P. Changes in gut microbes and host metabolism: squaring the circle?. Nat Rev Gastroenterol Hepatol 13, 563–564 (2016). https://doi.org/10.1038/nrgastro.2016.135

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